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For greater than a century, scientists have spotted water has a lot of atypical houses that don’t are compatible throughout the vintage fashion of it being only a forged, liquid or gasoline.

Gerald Pollack constructed upon the ones observations, and sooner or later decided that once a negatively charged floor is provide, if an acceptable calories supply could also be provide (specifically infrared — which is in all places), the water will compile itself into layers of offset hexagonal sheets with the system H₃O₂ that behave like a liquid crystal.

Be aware: Along with gentle, sound too can generate H₃O₂.

In my eyes, liquid crystalline water is a significantly underneath preferred house of science because it supplies a mechanism to provide an explanation for most of the unexplained mysteries of the frame (e.g., how do such a lot of fluids go with the flow inside it in spite of there being no identified pump to transport them) and a approach to put phrases into a lot of what we continuously apply throughout the frame.

What Is Liquid Crystalline Water?

Liquid crystalline water has an important level of solidity, and can expel maximum issues from coming into it (e.g., polystyrene microspheres), together with the displaced hydrogen atoms (as it’s H_1.5O no longer H₂O). Those displaced undoubtedly charged H atoms (henceforth known as protons), in flip compile in an instant outdoor this lattice, thereby making a pH and price gradient which can also be measured.

In lots of circumstances, those H₃O₂ lattices can also be huge — in favorable prerequisites, Pollack and others have measured ones starting from 0.1 millimeters to 0.5 millimeters (100,000 to 500,000 nanometers or nm) in length. Cells rely on this water, so that they comprise a lot of surfaces from which the water can shape.

For instance, 20% of the cellular is occupied via its cytoskeleton (a protein lattice which maintains its construction), and research of high-voltage electron micrographs have proven that throughout the cytoskeleton, over part of the water provide is inside 5 nm of a floor it would doubtlessly shape H₃O₂ on (for reference a unmarried H₂O molecule is 0.27 nm in length).

Because the floor websites that water can construction on are so intently packed in combination in cells, it’s comprehensible why liquid crystalline water (additionally regularly referred to as EZ water) could be so a lot more obvious to people gazing dwelling cells underneath a microscope (which in truth is the place a lot of the early analysis on H₃O₂ originated from). This in flip raises any other query: why are cells designed to create such a lot liquid crystalline water?

Be aware: An extended article describing the lengthy historical past of study into liquid crystalline water (H₃O₂) and its bodily houses can also be learn right here.

Mysteries of the Mobile

Within the earlier article, I mentioned a commonplace factor I apply inside science. When an fallacious fashion is applied to provide an explanation for a herbal procedure, discrepancies between the fashion’s predictions and truth will inevitably seem.

One would be expecting that once this occurs, it could inspire the ones espousing the misguided fashion to reconsider their fashion, however as a substitute, since such a lot has been invested into that fashion, they as a substitute will denounce any demanding situations to it, and get a hold of innumerable inventive tactics to provide an explanation for away each and every failure of the prevailing fashion.

Imagine, for instance, the preliminary guarantees of the vaccines (in the event you get two doses, you have been informed that you’d be utterly immune, transmission would prevent, and COVID-19 would all of a sudden fade into reminiscence). Because the medical trials for the vaccines have been fraudulent, not one of the vaccines’ guarantees materialized, and the COVID scenario as a substitute become worse.

Then again, as a substitute of healthcare government (and the scientific neighborhood) admitting their mistake and switching to another means for managing COVID-19, they doubled down at the vaccine mandates and moved the function posts time and again with regard to what mass-vaccination (and boosting) used to be if truth be told intended to perform.

Likewise, for cell biology, our wisdom of the cellular is unusually primitive and the prevailing fashions ceaselessly fail to provide an explanation for what happens throughout the cell setting. Then again, because the selection fashions aren’t normally approved via the clinical neighborhood, now we have been pressured to repeatedly patch the prevailing fashions in order that they may be able to slightly account for the innumerable mysteries of existence.

At this level, I consider one of the vital key reasons of this example is clinical analysis turning into distorted to prioritize that specialize in discoveries that trade can benefit from.

For instance, immunology has a slim center of attention at the facets of the immune device which can also be focused via vaccination or proprietary medicine, which in flip has left many different elements of the immune reaction disregarded (the immune device is regularly known as one of the vital least understood techniques within the frame).

In a similar way, since pharmaceutical medicine ceaselessly paintings via affecting receptors and channels in cells, cell biology has followed a narrow-minded center of attention on simply the ones facets of a cellular.

In flip, the liquid crystalline segment of water supplies a lot of explanations for most of the organic phenomena that the prevailing fashions merely don’t adequately deal with. On this article, I will be able to center of attention upon a couple of of them.

Be aware: A lot of what’s mentioned on this article is roofed in additional element inside those 3 books (in a similar way, the vast majority of the references for this newsletter are sourced from those books, so I will be able to no longer repetitively cite them right through the object). If you want to additional learn about the topic your self, I’d suggest studying the ones books (all authored via Gerald H. Pollack) on this order:

• The Fourth Segment of Water: Past Cast, Liquid, and Vapor (2013)
• Cells, Gels and the Engines of Lifestyles: A New, Unifying Way to Mobile Serve as (2001)
• Segment Transitions in Mobile Biology (2008) — that is probably the most technical of the 3

Cell Integrity

Probably the most primary puzzles of biology is the immense sturdiness that cells have. Should you imagine the vintage fashion — cells being luggage of liquid contained inside a fluid mosaic membrane, it must be easy for exterior forces to “pop” cells and feature all in their contents spill out. But typically, cells care for their integrity in spite of vital stressors.

Cells can live to tell the tale traumas, together with being guillotined in part, drawn and quartered (so particular elements can also be remoted and labored with — equivalent to when appearing in vitro fertilization), or shot filled with holes with electric bullets, each and every of which one would be expecting could be enough to “pop” them. Then again, in each and every example, cell integrity of the rest part persists.

In a similar way, if the membrane from a cellular is got rid of, its inner contents stay in position slightly than all of a sudden dispersing. It has additionally been identified for over 50 years that if muscle fibers lose their membranes, their practical talent (making a contractile power) stays intact.

3 clues assist to provide an explanation for those phenomena. The primary is that — as Pollack has proven — water droplets have a outstanding quantity of integrity, and prefer cells, will care for their integrity (and therefore fuse again in combination) if a micro-blade is used to guillotine them in part. The second one is that Pollack has additionally proven water droplets comprise an important level of liquid crystalline water which most likely is what confers their integrity.

The 3rd is that the water molecules in cells predominantly exist inside gels, that are composed of that very same liquid crystalline water. Put in a different way, which means that a cellular’s balance is in large part a belongings of its water keeping it in combination slightly than the exterior construction which encapsulates it.

Every other essential facet of cell structure must now be regarded as. Because the prerequisites for liquid crystalline water formation are provide right through the cellular (negatively charged hydrophilic surfaces and ambient infrared calories), the cells must all of a sudden be filling themselves with liquid crystalline water layers loads of micrometers in thickness.

But, right through the cells, the surfaces are ceaselessly best fractions of a micrometer aside. Which means that the construction of the cellular relies on the continuous formation of liquid crystalline water, however concurrently constrains that crystalline construction from rising to its complete length.

Tensegrity

Classically in structure, constructions are created via having sturdy skeletons upon which the remainder of the construction rests. For instance, within the outdated days, we continuously used stone pillars; in this day and age, skyscrapers require metal superstructures to fulfill the desires of those constructions:

This fashion ceaselessly does no longer paintings inside dwelling organisms, as a result of existence, in contrast to the ones constructions, calls for fast motion, and dwelling organisms merely can’t produce forged constructions with the similar energy as metal beams. Then again, another and extra complicated architectural fashion has been evolved which is continuously used by those that embody complexity inside their fashions.

Tensegrity (quick for tensional integrity), used to be a fashion first put ahead via Buckminster Fuller. It posits that if a chain of non-compressible constructions are related in combination via a lattice of elastic connections (which is able to retailer pressure when stretched), a far more potent construction is created.

It is because any power the construction receives will likely be similarly allotted via each and every of the ones elastic connections slightly than targeting a unmarried part (e.g., the stone pillar), and thus, a lot much less more likely to exceed the snapping point of any unmarried structural part.

Fuller’s paintings therefore impressed a lot of constructions to be constructed at the rules of tensegrity. It is a vintage image of him keeping a tensegrity sphere he made:

Biotensegrity encapsulates the conclusion that this identical device additionally happens right through nature. For the human frame, at each and every degree of group, a related tensile matrix is provide that confers its balance.

One French hand surgeon, Jean-Claude Guimberteau, has likewise achieved a outstanding process of demonstrating the presence of related tensile constructions on the degree of fascia (a connective tissue provide right through the frame many handbook therapists paintings with), via small (magnified) cameras positioned within the frame right through minimally invasive surgical procedures:

Be aware: On the magnification scale used right here and in his different movies, liquid crystalline water can also be without delay noticed coating those constructions. Additionally word its lubricating high quality that permits the constructions to slip previous each and every different. Lack of this lubrication seems to create a lot of problems throughout the frame.

Because the years move via, there seems to be a better consensus throughout the holistic scientific box that biotensegrity is a legitimate fashion for working out the frame, and that related networks of anxiety are provide from the biggest to the smallest ranges of the frame (e.g., the cytoskeleton is the elastic connecting unit inside each and every cellular). Then again, whilst this idea is continuously mentioned, there are nonetheless two primary unaddressed problems with it, which I consider liquid crystalline water can give an explanation for.

The primary is that during Guimberteau’s paintings, he had noticed that tiny vacuoles (enclosed compartments stuffed with water) right through the frame shape the fundamental incompressible unit that a lot of the frame’s tensegrity relies on.

The second one is that at a good upper magnification inside cells, whilst a cytoskeleton is provide this is underneath pressure, there may be not anything that may be noticed which creates that pressure (and it’s extremely arguable if the cellular’s connections to the extracellular matrix suffice to create that pressure). This issues since the structural energy of a tensegrity device best emerges when a construction’s elements are underneath pressure.

In terms of the previous, I consider that the microvacuoles are stuffed with liquid crystalline water (which can’t be compressed). In terms of water droplets, Pollack concluded that the mutual repulsion between undoubtedly charged protons (driven to the middle of the droplet via sheets of H₃O₂) creates an outwards power resisted via the liquid crystalline boundary of the droplet.

The steadiness between those two forces leads to the droplet assuming a round shape, and I consider the similar mechanism is at paintings within the microvacuoles right through the human frame.

In terms of the latter, you will need to consider how a lot growth is produced via proteins that create gels (many gels are over 99.9% water). Pollack, in flip, has proven that the liquid crystalline water this is continuously looking to shape throughout the cellular is not able to succeed in its complete length because of proteins resisting the stretch that must happen have been the liquid crystalline gel to develop to its complete length.

This occurs each on the degree of the cellular (because the cytoskeleton stretches because the cellular expands to its most length, till it can’t permit additional growth to happen) and inside proteins right through the cellular.

On the protein degree, the frame ceaselessly is based upon chemical bonds to be made between proteins to constrain the utmost growth that may happen according to a gel forming. Moreover, proteins can trade between a folded and an opened up conformation (e.g., a helix vs. a coil), one thing ceaselessly decided via the strain implemented to the protein (such because the expansive drive of liquid crystalline water inside a gel).

There are a selection of significance penalties of this conformation alternate which will likely be mentioned later on this article (e.g., for the body structure of muscular tissues). Moreover, many different elements of the frame additionally seem to depend upon liquid crystalline water:

“Learning collagen, Melacini et al. famous the significance of water in stabilizing its triple helix crystalline construction. They discovered that water throughout the collagen helix paperwork a “semi-clathrate-like construction that surrounds and interconnects triple helices within the crystal lattice.”

Water throughout the matrix of bone is likewise extremely structured, a structuring that has been discovered related no longer best with natural macromolecules equivalent to collagen and proteoglycans, however with the mineral surfaces as properly. Water, in truth, turns out to play a foundational function in orienting mineral nanoparticles into parallel preparations throughout the bone matrix, offering this orientation even within the absence of natural molecules.”

On a regular basis Gel Expansions

Many applied sciences we’re accustomed to (e.g., diapers) depend upon hydrogels which is able to extend right into a semisolid construction which retain water. In a similar way, we will without delay apply that many higher processes throughout the frame also are dependent upon water’s tendency to gather into the bigger liquid crystalline constructions.

For the reason that customary structure of protein’s cross-linking habits limits how a lot gels can extend (because the proteins which might wish to separate to house the rising gel are avoided from doing so via pass hyperlinks between them), when tissue or protein is broken, this limitation can also be partly got rid of. In consequence, it may be noticed on a microscopic scale that human tissue will swell and extend when it’s broken.

Likewise, Pollack has argued that that is possibly what occurs whilst you enjoy a musculoskeletal trauma. In Pollack’s proposed fashion, the preliminary gel formation additional expands the prevailing tear, and this modern growth of liquid crystalline water sooner or later ends up in visual swelling.

On a bigger scale, one of the vital primary engineering demanding situations for the frame is having weight-bearing joints just like the knees have the ability to care for their vary of movement with out turning into broken via the continuous friction they enjoy each day.

A outstanding function about liquid crystalline water is that, supplied the outside from which it paperwork stays intact, liquid crystalline water can also be destroyed after which reform, along side its nearly frictionless floor, again and again.

On account of this, the liquid crystalline water finally ends up being the part which absorbs the tension skilled via wholesome joints, and supplied the joint is wholesome, this water can immediately regenerate from that tension. Together with this regenerating layer of negatively charged liquid crystalline water, on the very middle of the joint, there’s a pocket of undoubtedly charged protons which repel from each and every different and create an expansive drive (like what’s noticed in a water droplet).

Because the joint pill seals this area, the ones protons are not able to flee and thus successfully serve as like repelling magnets (e.g., imagine a maglev educate) that face up to the burden of the frame and care for the central house throughout the joint.

Probably the most issues I imagine probably the most compelling about Pollack’s fashion for the joints is the precise high quality of synovial fluid throughout the knee joint. While you view it on a digital camera right through an arthroscopic surgical procedure, diffusion inside it’s visibly slowed, whilst in the event you without delay extract it (e.g., right through a knee aspiration), you’ll be able to inform that it has a far thicker and gelatinous high quality, one thing I’ve discovered to go along with the presence of liquid crystalline water.

Pollack likewise argues that his fashion suggests EZ (liquid crystalline) water’s habits resembles that of a gelatinous egg white which is semisolid when left on my own, but in a position to go with the flow according to an imposed shear power.

Cell Gradients

Be aware: A “gradient” describes a distinction within the focus of items in two other spaces. This would come with electric fees (i.e. batteries rely upon gradients), electrolytes, or temperatures — and lots of gradients supply an simply harvestable supply of calories.

The prevailing paradigm of physics asserts the next:

• The herbal state of items is to be disordered and calmly combined.
• Anytime you are making one thing develop into extra ordered (e.g., forming a crystal or making a gradient between two spaces), calories will have to be expended to create that ordering.
• When an ordered construction turns into disordered, calories is launched within the procedure which is able to every now and then be harvested (e.g., combusting wooden in a wooden range to warmth our houses).
• Anytime calories is launched from one thing, in the event you try to seize and retailer that calories, some calories will at all times be misplaced.

Those regulations, in flip, are used to refute the chance that any form of “free-energy” device can exist, such because the exclusion zone (EZ) water device Pollack has proposed the place a lot of harvestable gradients are created. Sadly for the prevailing paradigm, biology ceaselessly seems to violate those regulations, as it’s frequently transferring in opposition to a extra ordered state slightly than the disordered state the present paradigm predicts.

The present solution for this paradox (which gained a Nobel prize) is that dwelling organisms serve as as “dissipative constructions,” which trade the order in massive quantities of ordered elements they collect from their setting in go back for imparting order to their very own disordered contents.

Despite the fact that to some degree this permits the prevailing paradigm to maintain itself, I don’t consider it’s solely correct as water, via its liquid crystalline construction, has the power to retailer radiant calories that passes via it and convert that calories to reserve the frame can then make the most of.

The Sodium Potassium Gradient

Probably the most issues dwelling cells are widely recognized for doing is concentrating potassium within themselves and reciprocally expelling sodium. Because the focus outside and inside cells differs, a gradient exists, which, via the prevailing regulations of physics must attempt to equalize itself and all of a sudden disappear.

Since this doesn’t occur, the prevailing fashion has argued that the cell membrane prevents the passage of maximum however no longer all sodium and potassium (thereby inhibiting the gradient from equalizing itself) and that sodium potassium pumps at the cell membrane exist which power change sodium throughout the cellular for potassium outdoor the cellular.

As a result of this trade is so essential to keeping up the well being of the cellular, a big center of attention in cell biology is positioned at the significance of the sodium potassium trade pump. Sadly, there are 3 basic issues of this fashion (the proof of each and every of those and extra is gifted via Gilbert Ling right here):

• The mathematics does no longer upload up — the prevailing sodium potassium pumps merely do not need the capability to counteract the herbal undoing of the sodium and potassium gradients. For instance, in muscle cells, keeping up the sodium potassium gradient with pumps calls for between 4 to 30 occasions the general to be had calories within the cellular.
• Cells are in a position to care for a gradient with a lot of different unwanted elements they expel (e.g., micro organism expelling antibiotics) and to provide an explanation for those phenomena, an increasing number of pumps are known to check out to make stronger the fashion. It is a downside as a result of it’s not likely that cells have the capability to concurrently maintain such a lot of other pumps.
• Ling took frog muscle cells whose setting used to be altered in order that they have been utterly starved of calories (which is had to perform the sodium potassium pump). In spite of this, the gradient used to be maintained.

This then begs the query of what may well be growing this gradient? Ling made the next observations:

• The gradient used to be maintained if the cellular membrane (the place the ones pumps live) used to be got rid of.
• Generating a membrane with sodium potassium pumps that didn’t comprise a cytoplasm (the interior of a cellular) resulted within the gradient all of a sudden disappearing from with the membrane.

This implies that the gradient is a belongings of the cellular cytoplasm slightly than the cell membrane. Curiously, the an identical belongings has been present in synthetic gels, which just like the cytoplasm, additionally generate massive quantities of liquid crystalline water:

“We display that the gel barrier is in a position to care for a solid separation of ionic answers of various ionic strengths and chemical compositions with none pumping job. For the Na+ /Ok+ focus gradient sustained around the barrier, a adverse electrical possible develops throughout the Ok+ -rich facet. The location is harking back to that within the cellular.

Moreover, additionally the advective go with the flow of water molecules around the gel barrier is specific, in spite of the gel’s massive pores and the osmotic or hydrostatic drive gradients throughout it.”

This focus phenomenon has additionally been noticed via different authors:

“Proof for such accumulative condensation used to be produced nearly a century in the past when Bungenberg de Jong in 1932 confirmed that even dilute answers of polymers, when shaken, coalesced into droplets-then referred to as coascervates-in which the natural subject become extremely concentrated. The polymer focus in such droplets may exceed the focus within the surrounding tub via up to 10,000 occasions.

When positioned in sure dyes, the droplets become steadily extra coloured, the depth ceaselessly again and again exceeding that of the encompassing resolution. Thus, gel droplets had the capability to pay attention sure solutes, because the cellular concentrates potassium.”

Since gels independently show most of the inexplicable traits of cells, it’s thus affordable to conclude they could proportion a mechanism for generating the sodium potassium gradient noticed right through biology.

Obstacles

One primary problem for all cells is holding undesirable issues out. Classically, we view the method of pathogenic ingredients coming into cells as being a product in their interplay with matching receptors at the cells (a global view which I consider is emphasised via scientific science as a result of medicine can also be evolved to disrupt this procedure). I, in flip, consider that this exclusion procedure via the cellular is closely influenced via current fees, zeta possible and liquid crystalline water.

As a result of liquid crystalline water can for probably the most phase best shape on negatively charged surfaces (the similar means that water molecules each and every expel part a hydrogen atom and thereby cling a internet adverse price because of the misplaced hydrogens), nearly each and every floor within the frame (and lots of different herbal techniques) is lined with a adverse price.

Since colloidal balance (which governs the habits of maximum fluid techniques) in large part relies on the mutual repulsion created via an identical fees, maximum herbal colloidal techniques make the most of adverse fees to stay dispersed and best clump in combination if over the top certain fees are provide (likewise maximum strategies of restoring zeta possible perform in this concept).

Pathogenic organisms ceaselessly impart certain fees to their setting (equivalent to via micro organism decarboxylating the adverse fees of amino acids inside proteins). This reasons proteins and cells throughout the frame to start clumping in combination (the malaria parasite is especially excellent at doing this), which each prevents the immune device from getting access to the microbes and will increase the microbe’s talent to realize get admission to to the cells.

Probably the most specifically fascinating observations made via the unique proponent of physiologic zeta possible used to be that bacterial and viral infections (I consider this used to be probably the most studied with influenza) would create a constant degradation of the physiologic zeta possible. This offers an reason for why viruses like influenza can also be so a lot more bad for the aged.

Somebody with a wholesome zeta possible can tolerate a minor impairment in their colloidal balance (they’re going to simply really feel just a little in poor health), however for somebody who already has an impaired zeta possible (which is a quite common end result of growing old), that relief can also be enough to cross a important threshold the place critical sickness onsets.

Probably the most earliest distinguishing traits of COVID-19 to me used to be that many sufferers evolved medical indicators suggesting critical zeta possible disruption, one thing I had no longer noticed with some other breathing virus. A key reason why I used to be involved in regards to the spike protein lengthy sooner than the vaccines entered the marketplace, used to be as a result of I had known it because the most likely perpetrator for this zeta possible disruption.

This used to be because of it being a singular part of the SARS-CoV-2 virus (it differed from that of SARS-CoV-1) that used to be provide at the floor of the virus and which had an surprisingly excessive certain price density. It has since been proven that the spike protein without delay induces clumping of pink blood cells, most likely because of its price distribution having the prospective to create an important disruption of physiologic zeta possible.

Probably the most fascinating feedback I’ve many times noticed mentioned via each people who have taken protocols to give a boost to their frame’s manufacturing of liquid crystalline water and people who have achieved the similar for making improvements to their zeta possible, is they hardly ever get ill.

This would doubtlessly imply both that the indicators of infections are a lot more minor if those physiologic parameters are already in excellent well being (e.g., because you don’t cross a important zeta possible threshold), or as a result of they without delay save you cells from turning into inflamed via pathogens.

As many elements which undoubtedly impact one of the vital parameters ceaselessly impact the opposite (e.g., earthing improves zeta possible and promotes the expansion of liquid crystalline water within the frame), it’s just a little laborious to mention which impact in the end predominates, and a really perfect deal of my analysis in this matter used to be in accordance with attempting to respond to that query.

Be aware: The strategies of restoring zeta possible and lengthening liquid crystalline water throughout the frame are mentioned additional right here.

On this article, we evaluate probably the most proof supporting that barrier speculation. The earliest I got here throughout used to be from the paintings of Viktor Schauberger (1885-1958), who believed it used to be significantly essential for water to commute in a vortexing trend, one thing as mentioned within the earlier a part of this sequence, has been proven to extend the presence of liquid crystalline water.

Probably the most many discoveries made by using vortexing techniques in accordance with his design for water provides used to be that it lowered the expansion of micro organism throughout the water device (e.g., at the within pipes).

Different analysis has without delay discovered that the presence of liquid crystalline water prevents the expansion and invasion of micro organism, equivalent to this learn about:

“In a check carried out with E. coli, cells steadily penetrated EZ [liquid crystalline water] over 2 days. Moreover, EZ-bearing Nafion had 80% much less biomass accumulation of E. coli over 2 days in comparison to an EZ-less, hydrophilic, easy aluminum oxide floor. This implies that EZ would possibly constitute the primary defensive position, spatially and temporally, in opposition to micro organism drawing near sure hydrophilic surfaces.

Those findings will have essential implications in growing biofouling-resistant subject material surfaces for packages delicate to bacterial attachment and biofilm formation.”

And this learn about:

“Silk sericin is a globular protein whose resistance in opposition to fouling is essential for packages in biomaterials and water-purification membranes. Right here it’s proven how sericin generates a water-exclusion [liquid crystalline] zone that can facilitate antifouling habits. Negatively charged microspheres have been used to imitate the outside price and hydrophobic domain names in micro organism.

Immersed in water, sericin shaped a 100-µm-sized exclusion zone (for micron-size foulants), along side a proton gradient with a lower of >2 pH-units. Thus, when in touch with sericin, water molecules close to the outside restructure to shape a bodily exclusionary barrier that may save you biofouling.

The diminished pH turns the aqueous medium unviable for neutrophilic micro organism. Due to this fact, resistance to biofouling turns out explainable, amongst different elements, at the foundation of water-exclusionary phenomena.”

Many tissues rely at the presence of liquid crystalline water lining them, and that is most likely no less than partially, because of the protecting barrier they devise. Inexperienced and Otori in 1970, for instance, discovered exclusion zones roughly 350 μm deep extending from the cornea, and in addition from touch lenses (it’s essential to give protection to the attention from injury, and liquid crystalline water purposes as a clear, well-lubricated barrier, qualities each important for the eyes).

Pollack, roughly 15 years in the past, additionally discovered an identical effects (the presence of liquid crystalline water) subsequent to polyNIPAM, the gel used to manufacture touch lenses.

One of the vital essential tissues within the frame for offering a protecting (however well-lubricated layer) is at the endothelial lining of the blood vessels. There, massive quantities of blood growing vital shear forces continuously cross over the blood vessels. Thus far, Malcom Kendrick has famous that the spaces of movement which enjoy the best shear forces are the possibly to broaden the power injury which sooner or later ends up in middle illness.

The protecting coating of the endothelium, the glycocalyx, is structured (because of its excessive sulfate content material) to create massive quantities of gel (liquid crystalline water) round it and thus offer protection to the endothelium. Moreover, a skinny layer that blood cells can’t input is understood to without delay line the partitions of even the smallest blood vessels.

In a similar way, researchers in 2000 noticed a nil.4-0.5μm thick gelled layer of water lining the endothelium of wholesome capillaries (the smallest blood vessels within the frame), and this lining excludes a lot of other ingredients from attaining the endothelium.

Formally, the vaccine spike protein can’t impact the endothelium as it lacks a practical ACE2 binding area (while the COVID-19 virus has a practical one during which it then enters the cellular).

Despite the fact that that is the case, there are many alternative ways that the spike protein can nonetheless connect to the endothelium (e.g., the spike protein can nonetheless connect to the receptor, it without delay binds heparin within the glyocalyx, and whether it is made out of throughout the endothelium via the vaccine, it has successfully entered the endothelium).

Since autopsies of people suspected to have died because of vaccination have printed profound injury to the endothelial layer, this offers sturdy proof that the spike protein in a technique or any other has the power to penetrate the generally protecting barrier there.

Many have suspected that that is partially because of the extremely certain price that the spike protein (and the every now and then undoubtedly charged elements of the lipid nanoparticles) carries, as those certain fees can penetrate the liquid crystalline water barrier protective cells just like the endothelium.

I consider it will also be because of the spike protein’s disruption of zeta possible, as different states related to higher blood viscosity (e.g., out of control diabetes) are identified to injury the endothelium and boost up the development to heart problems.

Segment Transitions

Despite the fact that liquid crystalline water is essential for existence, an excessive amount of of it will also be problematic. For instance, if all the cellular used to be lined with gel-state water, it could no longer be imaginable for plenty of issues that wanted to go into the cellular to go into.

To unravel this downside, spaces of certain price exist within the membrane (e.g., Pollack argues that it is a key reason why for the position of steel ions throughout the cellular membrane), which stop liquid crystalline water from forming over the world and thus create an open passage for water to commute via.

Be aware: Despite the fact that we’re taught to consider the cellular as a fluid mosaic of phospholipids with proteins right here and there, roughly 50% of the cellular membrane is most often composed of proteins (and it may possibly every now and then be much more).

Generally, alternatively, the frame is based upon having the ability to change into water between its gel (liquid crystalline) state and a sol (bulk water containing colloidal suspensions) state as wanted. Then again, whilst reputation of the elemental significance of segment adjustments in cell biology has regularly higher during the last 70 years, the vast majority of the clinical box continues to be wedded to the fluid mosaic speculation, which believes that the cell membrane is at all times a liquid.

In brief, gels (each herbal and artificial ones) most often have a temperature (its transition level) the place the gel will go through a fast transition from one state to the opposite (defined additional right here). So far as I do know, in all circumstances, the warmer temperature will correspond to the sol state (H₂O water with suspended colloids) and the chillier one will correspond to the gel state (H₃O₂). Moreover, higher drive may even advertise the gel state:

“Organic job nearly universally calls for that membranes be of their fluid state; in lots of circumstances, simply above the transition level.”

Gels right through the frame, in flip, are designed to have a segment transition level close to the standard temperature of the frame. This will give an explanation for why maximum mammals and birds care for their temperature between 35°– 42°C (95°– 107.6°F; the standard temperature for people is 37°C or 98.6°F), an differently curious reality given how a lot their our bodies and environments fluctuate (e.g., a tiny hen within the wasteland vs. a blue whale).

Moreover, this temperature extends past warm-blooded animals. A tuna fish, when energetic, maintains the temperature of its frame at 30°C or 86°F (the sea is far chillier) whilst many reptiles care for their frame temperature close to 40°C or 104°F (via doing such things as in quest of out the solar). Many bugs additionally can’t fly till they’ve warmed as much as a equivalent vary of temperature (e.g., 38°C or 100.4°F for bumblebees).

In a similar way, the segment transition level is closely influenced via the fabrics that the gel builds from (e.g., elements of the cellular membrane). Chilly-blooded animals in flip had been noticed to switch the composition in their cellular membranes according to their setting.

In a single experiment, Calotes versicolor (the average lawn lizard), have been acclimatized to 16°, 26°, and 36°C (60.8°, 78.8°, and 96.8°F) for a length of thirty days. The lizards exhibited dramatic adjustments within the focus of primary phospholipids (elements of the cellular membrane) equivalent to phosphatidylcholine, phosphatidylethanolamine, phosphatidylinositol, cardiolipin, and sphingomyelin.

Temperature acclimatization has additionally been noticed to alter the lipid composition of carp muscle microsomes along side carp blood cells, and seasonal variation has been noticed within the lipid composition of brains of rainbow trout.

As soon as the gel is held close to its transition temperature, it’s then relative simple to switch precisely the place that transition temperature is so water can also be stored in the best segment for the present physiologic wishes. That is essentially achieved throughout the frame via converting the electrolyte composition of the world, as sturdy cations (undoubtedly charged ions) smash gels, whilst sturdy anions (negatively charged ions) toughen them.

So far as I will inform, the results of those ions correlate to the excessive valence (price) anions (-) that the majority successfully make stronger physiologic zeta possible and the ones excessive valence cations (+) which maximum successfully smash it.

The principle cation component which the frame makes use of to shift the transition temperature with the intention to smash gels is calcium (Ca). As an instance the impact of calcium graphically (word how a unexpected important threshold of Ca focus is reached):

Those effects additionally confirmed how the upper valence cations, Ca²⁺, reason smaller gels to shape relative to low valence cations Na⁽¹⁾⁺.

When you put all of this in combination, you successfully get a scenario like this throughout the cells which permits small secretions of calcium there to shift its water from a fluid to a gel state.

Conversely, if the frame can disperse the gels, it additionally wishes a approach to recreate them. The principle sturdy (excessive valence) anion it makes use of to construct them are the phosphates in adenosine triphosphate (ATP).

Once we imagine this selection serve as of ATP, we must imagine probably the most concepts first proposed via Ling (see 8.4 on web page 178). They counsel that a lot of the calories bought from ATP arises no longer from the calories inside its bonds being damaged, however slightly from it inducing water to shape a liquid crystalline construction. In essence, a lot of the calories generated from ATP in the end arises from the radiant calories which triggers those polymerizations (gels).

Segment transitions are quite common in cell biology, and whilst the sphere does no longer position a heavy emphasis on their significance, Pollack’s central argument in his first two books is that segment transitions are essential to provide an explanation for many purposes of the cellular.

Be aware: After I later mentioned my articles with Pollack, he knowledgeable me that the principle oversight along with his previous analysis used to be that that they didn’t but know that the gels have been negatively charged, which in flip explains a lot of the results they devise (e.g., {the electrical} impulse of nerves).

Increasing Gels

Probably the most number one makes use of for gels throughout the frame is from them to all of a sudden extend and create results from that growth. For instance, cells continuously excrete small spheres (referred to as vesicles) containing essential elements, which upon exiting the cellular all of a sudden extend. Remoted mucin-producing vessels for instance go through a 600 fold growth in 40 milliseconds.

Previous to exiting the cellular, the interior elements of the vesicle are pass related in combination via Ca²⁺ (consider, upper valence cations, via crosslinking gel proteins, will restrict gel formation whilst monovalent cations like sodium as a substitute have a tendency to extend them).

As soon as secreted from the cellular, Ca²⁺ is got rid of and the gel all of a sudden hydrates within the Na⁽¹⁾⁺ resolution surrounding each and every cellular. Conversely, gels is not going to all of a sudden extend in distilled water, and it’s been noticed that liquid crystalline water’s formation could also be lowered inside deionized water.

Be aware: Some vesicles make the most of native environmental elements to switch their segment. For instance, histamine is a monovalent cation (price of +1) at a impartial pH, however turns into a divalent cation (price of +2) in an acidic pH. Researchers have been in a position to turn that histamine in an acidic setting (because of its excessive valence state), reasons shrinking of mast cellular granules, whilst histamine in a impartial setting permits their growth.

Muscle Body structure

Most of the maximum commonplace issues for which sufferers search out physicians originate from the muscular tissues. On account of this, I’ve checked out numerous other ways to regard the ones problems. In flip, I’ve discovered fairly a couple of that constantly paintings however I will not give an explanation for why as the prevailing fashion of muscle body structure can’t supply an evidence.

Probably the most primary issues of medication (and ceaselessly science) is what I time period the “mechanistic entice.” In brief it signifies that if there isn’t a mechanism to provide an explanation for why one thing works, then it’s assumed to be a hoax and idea not to if truth be told paintings. I feel this compulsive want for a fashion is fairly silly, particularly since most of the fashions we make the most of to provide an explanation for why medicine paintings, don’t if truth be told make sense.

In a similar way, there are lots of circumstances of a prior to now approved fashion for a drug’s mechanism that used to be discarded and changed with any other, and I do know of many extra examples the place an unorthodox fashion seems to offer a a lot better reason for the mechanism of a remedy.

Be aware: This additionally holds true for plenty of selection non-drug remedies.

Sadly, it’s just about unattainable to have the FDA (or many conventionally skilled physicians) be open to bearing in mind a remedy for analysis until a biochemical mechanism for it’s proposed. I consider it is a mirrored image of the reality pharmaceutical medicine, as they’re designed to focus on sure enzymes within the frame, are compatible into our inflexible mechanistic paradigm, whilst remedies with a vast spectrum of motion can’t be related to a particular biochemical receptor nor as simply profited from.

Given all of this, I used to be thrilled to find via Pollack that many facets of the prevailing fashion for muscle body structure don’t make sense, and the anticipated result of the fashion don’t happen when rigorous experiments on muscular tissues are carried out:

Then again, another fashion for muscle body structure additionally exists. As we imagine it, we must needless to say muscular tissues are known to simply be able to contracting. Within the cases the place one thing within the frame wishes to elongate, that is completed via having a muscle in the fitting position shorten, and because of its place, create a lengthening in different places via doing so (e.g., the triceps within the arm).

From Pollack’s paintings, I noticed that whilst muscular tissues can best create power right through a contraction, that is if truth be told a results of the reality their elements can best forcefully extend.

Pollack’s fashion is in accordance with the commentary that comfortable muscular tissues comprise a considerable amount of structured water, while contracting muscular tissues essentially comprise water no longer in a semisolid gel state. Since it’s identified that muscle firing follows the nerve sign directing calcium (Ca²⁺) ions to go into the muscle, this means a calcium brought about segment alternate would possibly underlie the method.

Conversely, it is usually identified (from the experiment prior to now described within the gradient phase) that whilst muscle cells that have been reduce open can retain their potassium to sodium gradient whilst in a salt resolution, the portions that lack ATP are not able to.

This implies that ATP is essential for the liquid crystalline state of water to be provide, because it excludes sodium ions from coming into the muscle cells. In a similar way, it is usually identified that with out ATP, muscular tissues will stay caught within the shriveled shape and be not able to elongate, one thing that happens in a while after dying (termed “rigor mortis”).

Be aware: Probably the most compelling anecdotal tales I’ve heard through the years is that once critically vaccine-injured kids die (e.g., the ones with lifelong debilitating autism) rigor mortis units in a lot sooner for them. Those that noticed this recommended that those kids had a prolonged calories deficit, and their our bodies have been suffering to make sufficient ATP to get via. I feel that is very imaginable, but it surely may be indicative of deficient zeta possible.

I think this may additionally be noticed with different power debilitating sicknesses, however I’ve no longer interacted with the individuals who would have noticed if it did in truth happen.

Pollack additionally noticed that muscle adjustments according to environmental elements adopted a well-recognized important threshold being handed. This additionally gave the impression to counsel to Pollack {that a} segment alternate used to be happening throughout the muscular tissues.

So what’s Pollack’s fashion? The muscular tissues fibers are designed to shape massive gels round them, and as liquid crystalline water inside them expands, it stretches the uncoiled proteins within the fibers into helixes (till protein pass hyperlinks save you additional stretching). When the muscle must contract, calcium ions input the muscle, getting rid of the gels, and the proteins not being lengthened elastically snap again to their unique uncoiled configuration.

To ensure that the gel to rebuild, ATP is needed to wreck the pass hyperlinks created via calcium and thereby cause a segment shift that reconstructs the gel.

Thus, the energy of a muscle is a made of the prospective calories created via liquid crystalline water’s garage of radiant calories being launched. Or put in a different way, the energy of muscular tissues if truth be told lies of their talent to spontaneously extend and explains why many efficient muscular remedies I’ve come throughout paintings.

Huge mechanical shear reasons the cytoskeleton matrix [another key structure that expands and contracts in response to phase changes] to fluidize, a phenomenon very similar to bodily rejuvenation in SGM’s [certain synthetic materials]. This fluidization is adopted via a sluggish scale- loose restoration of mechanical houses, a phenomenon very similar to bodily growing old in SGMs.

Unusually according to a temporary stretch, the cytoskeleton fluidizes in a trend this is common for various cellular varieties. This discovering implicates mechanisms mediated no longer such a lot via particular signaling pathways, as it’s normally assumed, however slightly – as we give an explanation for under – via non-specific movements of bodily forces.

Many different constructions additionally have the opportunity for his or her inner gels to reason growth and contraction, however in contrast to skeletal muscular tissues, typically, this growth and contraction isn’t as tightly constrained as what’s noticed throughout the closely cross-linked skeletal muscular tissues.

Clean muscular tissues, in addition to contractile rings, artificial actin gels (actin is likely one of the maximum commonplace contractile proteins within the frame), and different organelles with few covalent pass hyperlinks and semi-random constructions are different examples of puts the place the frame makes use of this concept to maintain existence.

Finally, it has additionally been noticed that converting the encompassing concentrations of salinity round different fibers (e.g., collagen) can lead them to extend and contract to the purpose they may be able to generate a power yielding contraction very similar to that of a muscle fiber.

Conclusion

There were a couple of central questions I’ve sought to handle in my exploration of liquid crystalline water. On this sequence, I sought a mechanism to provide an explanation for the commentary in a lot of conventional scientific techniques that an inherent expansive power exists right through the frame which performs a key function in offering its power and that once this expansive power is compromised, a lot of sicknesses set in.

I believe this trust and feature noticed a lot of cases the place it become imaginable to acknowledge the place that existence maintaining growth have been changed with a good compacted house, and in addition noticed strategies that sought to revive that growth additionally repair a affected person’s power.

Conversely, I consider the lack of mobility and sturdiness that accompanies growing old (and one of the vital greatest issues to elder sufferers) is without delay associated with the lack of liquid crystalline water we most often enjoy with age.

On this article, I’ve attempted for example the structural results of liquid crystalline water throughout the frame, and it’s my hope that via doing so, I’ve supplied a mechanism to provide an explanation for the place that expansive power originates from. Within the subsequent a part of this sequence, I give an explanation for how water’s liquid crystalline state creates a gradient that may be harvested for calories and creates the movement existence relies on.

Within the article after that, I did my best possible to provide an explanation for the intertwined courting between liquid crystalline water and zeta possible, and within the ultimate a part of this sequence I mentioned the strategies I’ve come throughout which seem to revive both.

Every of those subjects is fairly complicated (e.g., this newsletter used to be a synthesis of a lot of books and articles), however in my view nevertheless an important to dive into for unravelling the mysteries of existence. In flip, it’s my honest hope the well-liked awakening that has came about in our society on account of COVID-19 can re-light interest to discover unconventional topics like this.

I thank each and every of you for the eye you gave in looking to working out this reasonably complicated matter which is close to and costly to my middle. I sincerely hope that you may as well undertake a few of its implications into your day-to-day existence.

A Be aware From Dr. Mercola Concerning the Creator

A Midwestern Physician (AMD) is a board-certified doctor within the Midwest and an established reader of Mercola.com. I recognize his remarkable perception on a variety of subjects and I am thankful to proportion them. I additionally appreciate his want to stay nameless as he’s nonetheless at the entrance strains treating sufferers. To seek out extra of AMD’s paintings, be sure that to take a look at The Forgotten Facet of Medication on Substack.

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