Of the entire miraculous results skilled upon restoring the gastrointestinal (GI) microbe misplaced by way of the majority of us, Lactobacillus reuteri, I’ve no longer mentioned the rise in muscular tissues that happens with re-implantation of this microbe, an impact mediated by way of the spice up within the hormone, oxytocin.

We see this in animal experiments wherein aged mice with marked muscle atrophy—lack of muscle cells, shrunken muscle cells—have muscle restored to that approximating younger mice, reversing the sarcopenia (lack of muscular tissues) of growing older. We noticed this in our human scientific trial wherein individuals skilled a whole shift in frame composition with lack of stomach fats however building up in muscular tissues. We additionally see this, even though variably, in our actual international L. reuteri yogurt enjoy. (Why is the reaction variable? Does complete impact require microbial species to “collaborate” with L. reuteri? Variation within the oxytocin receptor? That is one thing I’d love to discover in long run animal and human experiments we will be able to behavior.)

Elabd 2014. At the left is a cross-section of muscle from an aged mouse. At the proper is a cross-section of muscle in an aged mouse given supplemental oxytocin with glaring recovery of plump full-volume muscle cells indistinguishable from that of a tender mouse.

I can’t pressure how essential it’s to handle younger muscular tissues. We lose roughly 35% of muscle as we age. You simplest want discuss with your nearest assisted dwelling facility to peer the end-result: atrophied legs and arms, issue status up immediately and strolling, incapability to climb stairs, frailty, susceptibility to falls and fractures, metabolic deterioration, lack of hormonal well being—in a phrase, bad growing older accompanied by way of reliance on canes, walkers, scooters, wheelchairs and larger dependence on prescription drugs to make amends for deteriorating well being. Can there be a lot pride upon achieving, say, age 80 however depending on lend a hand to get off the bed, use the bathroom, a walker to get to the breakfast room, prescription drugs (e.g., metformin for blood sugar, beta blockers or ACE inhibitors for high blood pressure, Vascepa for top triglycerides, Namenda for cognitive decline, and the entire different terrible merchandise that constitute little greater than Band-Aids for growing older)?

Just about all standard strategies for shedding pounds make the placement worse. In case you shed some pounds by way of decreasing energy, or by means of pharmaceuticals together with the absurd craze over GLP-1 agonists like Ozempic, Wegovy, or Mounjaro, or bariatric procedures like lap-band or gastric bypass, about 25-40% of weight reduction is muscle loss. In case you misplaced, say, 50 kilos, you might have misplaced about 17-20 kilos of muscle, a massive loss chargeable for a big downturn in total well being. And, when (no longer if, as weight regain is the guideline with all of those strategies) you regain the misplaced weight, maximum of it’s fats, no longer muscle and you’re unhealthier than you had been initially. Simply watch as this craze over GLP-1 agonists and bariatric procedures proceeds and other folks notice that they’ve been hoodwinked for the monetary advantage of the healthcare machine.

I skilled the recovery of younger muscle for my part once I first restored L. reuteri by means of my distinctive manner of extended fermentation to generate loads of billions of bacterial counts. Monitoring frame composition by means of a bioimpedance scale, I won 13 kilos over the primary 3 weeks of intake accompanied by way of a discount in waist circumference. It’s not that i am in particular keen on going to the health club, so I’m going about as soon as every week for 15-20 mins to make use of the load machines. I usually treated weights like 130 kilos in a lat pulldown for 10 repetitions. This promptly larger to 200 kilos for 10 repetitions, weight I had closing treated 40+ years previous at age 19. My suspicion is that the spice up in oxytocin skilled with recovery of L. reuteri approach you enjoy recovery of muscle you had while you had been more youthful—when you had been extra closely muscled all the way through your more youthful years, you’re more likely to regain extra muscle than folks. In case you had been an athlete, as an example, and loved larger power and muscular tissues at age 18 or 20, you’re more likely to enjoy a bigger impact than folks. I noticed this play out, as an example, in a scientist and previous particular forces soldier who I hadn’t observed in a couple of years. At age 67, he was once fairly closely muscled, indisputably greater than you’d be expecting for anyone his age. I requested if he’d been understanding and he instructed me that he was once incapable of power coaching since he broken each shoulders years previous, no longer even in a position to doing a unmarried pushup, despite the fact that he appeared like he spent hours per week on the health club. However he was once engaged within the L. reuteri yogurt and its oxytocin spice up.

Mix the recovery of L. reuteri with collagen peptides that you just had been intended to ingest by way of eating organs and boiling the carcass of animals and you have got a spectacularly efficient manner of restoring younger frame composition.

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